Recombinant protein products

Name Human TNF-alpha / TNFA Protein/重组人 TNF-alpha /
Specifications 20ug
Serial number CZDB-006
The price Inquiry
Chinese name Human TNF-alpha / TNFA Protein/重组人 TNF-alpha /
Molecular nickname TNF-alpha, TNF-a, Cachectin, DIF, TNFA, TNFSF2
Molecular species Mouse
Express label His,S
Express the host E. coli
Concentration > 95 % as determined by SDS-PAGE
Buffer Lyophilized from sterile PBS, pH 7.4
Storage conditions -70°C,应避免反复冻融。
Basic description Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.

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